Hemodynamic responses are abnormal in isolated cervical dystonia

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GABAA Receptor Availability Changes Underlie Symptoms in Isolated Cervical Dystonia

1 Department of Neurology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, 2 Department of Radiology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, 3 Neurology Section, Denver VA Medical Center, Denver, CO, United States, 4 Department of Psychiatry, School of Medicine, Stony Brook University, Stony B...

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Cervical Dystonia

There is now strong evidence demonstrating that bilateral globus pallidus internus (GPi) stimulation improves motor function and disability in patients with severe primary generalised, segmental or cervical dystonia. The improvement is gradual, typically occurring over a period of about six months, with pain and then phasic components dissipating before the tonic elements of dystonia. Controlle...

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Abnormal cerebellar signaling induces dystonia in mice.

Dystonia is a relatively common neurological syndrome characterized by twisting movements or sustained abnormal postures. Although the basal ganglia have been implicated in the expression of dystonia, recent evidence suggests that abnormal cerebellar function is also involved. In these studies, a novel mouse model was developed to study the role of the cerebellum in dystonia. Microinjection of ...

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ژورنال

عنوان ژورنال: Journal of Neuroscience Research

سال: 2019

ISSN: 0360-4012,1097-4547

DOI: 10.1002/jnr.24547